• Iran's Khamenei doubts the success of nuclear negotiations with the US.
• The fifth round of talks is set for May 23 in Rome, mediated by Oman.
• Iran insists on maintaining its uranium enrichment program, despite US demands.
• American officials assert that any deal must halt Iran's nuclear enrichment.
• Both nations remain divided over key issues, heightening tensions.

Iran’s Supreme Leader, Ayatollah Ali Khamenei, expressed skepticism about the viability of ongoing nuclear negotiations with the United States, stating, “We don’t think it will lead to any outcome. We don’t know what will happen.” Khamenei highlighted the importance of acknowledging Iran's right to enrich uranium, labeling attempts to deny this right as “a big mistake,” which underscores the growing discord between the two nations amid stalled diplomatic efforts, according to Dawn, India Times, and TRT Global.

The upcoming fifth round of talks is scheduled for May 23 in Rome, as confirmed by Oman's Foreign Minister Badr Albusaidi. This mediating role underscores Oman's long-standing commitment to enhance dialogue between the adversarial nations. Iran has confirmed its participation, and according to Foreign Ministry spokesman Esmaeil Baqaei, Tehran aims to negotiate sanctions relief in exchange for limiting its nuclear program, according to Al Jazeera and LA Times.

Despite these negotiations, tensions remain high as the US demands a complete halt to Iran's uranium enrichment, a condition Iran vehemently rejects. Foreign Minister Abbas Araghchi reiterated, “Uranium enrichment in Iran will continue — with or without an agreement.” This stance reflects the Islamic Republic's steadfast position amidst perceived threats from American officials, including President Trump, regarding military action if negotiations collapse, according to India Times and Newsweek.

Western nations, particularly the US, remain skeptical of Iran's intentions, suspecting that its nuclear program may be aimed at developing weapons capabilities, a claim Iran denies. The current state of affairs highlights a significant gap in expectations, especially concerning Iran's enrichment capabilities, which is seen as a "red line" by the US, according to TRT Global and Channel News Asia.