• Eric Dane died at the age of 53 after a battle with ALS.
• He was known for his roles in 'Grey's Anatomy' as Dr. Mark Sloan and 'Euphoria' as Cal Jacobs.
• Dane became an advocate for ALS awareness following his diagnosis in April 2025.
• His family reported he passed surrounded by loved ones, including his two daughters.
• Numerous celebrities have expressed their grief and admiration for Dane's spirit and talent.

Eric Dane, the actor best known for his roles on Grey's Anatomy and Euphoria, has died at the age of 53. His family announced that he passed away on February 19, less than a year after revealing his diagnosis with amyotrophic lateral sclerosis (ALS). "Eric Dane passed on Thursday afternoon following a courageous battle with ALS," the family stated, thanking fans for their support during his illness, according to BBC, Los Angeles Times, and CBS News.

Dane was renowned for his role as Dr. Mark Sloan, nicknamed "McSteamy," on the hit show Grey's Anatomy, a character that became a fan favorite from his introduction in 2006 until he left the series in 2012. Later, he starred as Cal Jacobs on HBO's Euphoria. His work on television led to a devoted fanbase and numerous accolades throughout his career, reports Channel News Asia, South China Morning Post, and Reuters.

Diagnosed with ALS in April 2025, Dane subsequently became a passionate advocate for raising awareness about the disease, which deteriorates muscle control and communication. Throughout his last months, he channeled his experiences into activism, vowing to help fund research and support for those facing ALS, according to a statement by his family and coverage by Le Monde and NPR.

In his final days, Dane spent time with family, including his daughters Billie and Georgia, who were described as "the center of his world." His wife, Rebecca Gayheart, although separated, remained a significant part of his life and care, demonstrating a "familial love" as highlighted in statements about their relationship. Gayheart remarked on the complexity of their bond following Dane's diagnosis, emphasizing mutual support, according to Los Angeles Times, South China Morning Post, and Le Monde.

Following his passing, many celebrities expressed their grief and pride in Dane’s courage, describing him as a beloved figure in their lives. Alyssa Milano, a co-star from Charmed, shared memories of his humor and spirit. HBO Max and the show's creator, Sam Levinson, praised Dane for his professionalism and kindness during their collaborations, underscoring the loss felt throughout the entertainment industry, as reported by Los Angeles Times and South China Morning Post.