• Investigators believe Nancy Guthrie was abducted from her home in Tucson, Arizona.
• No suspects or persons of interest have been identified in the ongoing investigation.
• Public assistance is sought, with authorities reviewing potential ransom notes related to her disappearance.

Authorities are intensifying their search efforts for Nancy Guthrie, mother of "Today" show host Savannah Guthrie, who is believed to have been abducted from her Tucson home over the weekend. Pima County Sheriff Chris Nanos confirmed that investigators have not identified any suspects or persons of interest as of now, despite the case being treated as a crime scene, due to concerning circumstances found at her home shortly after she was reported missing on Sunday morning, according to CBS News and ABC News.

Nancy Guthrie, 84, was last seen around 9:30 PM on Saturday, when her family dropped her off at home. Alarm bells rang around 11 AM Sunday, when a church member reported her missing, prompting a search and the discovery of potential evidence suggesting she may have been forcibly taken, according to reports from NPR and Los Angeles Times.

The sheriff has emphasized the urgency of the situation, as Nancy requires daily medication, which could be life-threatening if not taken. "We do believe Nancy was taken from her home against her will," he stated, indicating the severity of the crime, according to BBC and Los Angeles Times.

In the wake of the ongoing investigation, investigators are exploring the possibility that ransom notes may exist, although their authenticity remains unconfirmed. The department has also solicited public assistance, urging anyone with information to come forward, as they are actively pursuing every lead in this case, as noted by ABC News and NPR.

With approximately 100 detectives engaged and the FBI involved, efforts are expansive, including the use of dogs, drones, and helicopters for search operations. Sheriff Nanos has stated that Nancy's life is at risk without her medication, which adds to the urgency of finding her quickly, according to Los Angeles Times and BBC.